Anti-HIV API Lopinavir USP42 Powder with CAS 192725-17-0

• CAS No.: 192725-17-0
• Formula: 192725-17-0
• EINECS: 192725-17-0
• Grade: Pharm
• Function: Pharm
• Certification: MSDS, GMP, Halal
• Model NO.: Lopinavir
• Usage: Pharm
• Raw Material: 192725-17-0
• Transport Machine: Ordinary Goods Truck
• Appearance: White Powder
• Transport Package: Drum
• Specification: 99%
• Trademark: Recedar
• Origin: China
• HS Code: 1302
• Production Capacity: 1000t

Product Description

Anti-HIV API Lopinavir USP42 powder with CAS 192725-17-0

Product Name: Lopinavir
Synonyms:LOPINAVIR;(2s)-n-[(2r,4s,5s)-5-[[2-(2,6-dimethylphenoxy)acetyl]amino]-4-hydroxy-1,6-diphenyl-hexan-2-yl]-3-methyl-2-(2-oxo-1,3-diazinan-1-yl)butanamide;(aS)-N-[(1S,3S,4S)-4-[[2-(2,6-Dimethylphenoxy)acetyl]amino]-3-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]tetrahydro-a-(1-methylethyl)-2-oxo-1(2H)-Pyrimidineacetamide;A 157378.0;ABT 378;Aluviran;Koletr;(2S)-N-[(2R,4S,5S)-5-[[2-(2,6-Dimethylphenoxy)acetyl]amino]-4-hydroxy-1,6-diphenyl-hexan-2-yl]-3-methyl-2-(2-oxo-1,3-diazinan-1-yl)butanamide
CAS: 192725-17-0
MF: C37H48N4O5
MW: 628.8
Product Categories: Anti-viral Compounds;Anti-virals;Intermediates & Fine Chemicals;Non-nucleoside Reverse Transcriptase;Pharmaceuticals;Chiral Reagents;Pepetides;ProteaseInhibitors;API;peptides;ABT-378;Other APIs
Chemical Properties White Crystalline Solid
Usage A selective HIV protease inhibitor. An analogue of Ritonavir. Antiviral.
Usage Lopinavir is a potent HIV protease inhibitor with Ki of 1.3 pM
 

Lopinavir/Ritonavir tablets are a compound preparation of two drugs, lopinavir and ritonavir, both of which are viral reverse transcription inhibitors, of which lopinavir is the main drug. Protease binding makes the resulting virus particles immature and non-infectious; while ritonavir can inhibit the metabolism of lopinavir in the liver, thereby increasing the blood concentration of lopinavir and exerting a synergistic effect.

Package	carton drum with two plastic bags inside
Net weight	25KG/Drum
Storage	Sealed in cool and dry place to avoid moisture and light
Shelf life	2 years when properly stored
Lead time	1~3 days after confirmation

 

Analysis Items	Specifications
Appearance	White powder
Indentification	HPLC: The retention time of the test sample corresponds to that of the reference standard. IR: The infrared absorption spectrum of the test sample is concordant with the spectrum of reference standard
Water Content( by KF)	≤4.4%
Residue on igniton	≤0.20%
Heavy metals	≤20ppm
Related substance	Impurity 1	Impurity b(RRT=0.07)≤0.20%
		Impurity i(RRT=1.10)≤0.20%
		Any other impurity≤0.10%
	Impurity 2	Any other individual impurity≤0.10%
	Total impuriy from Procedure 1 and Procedure 2: ≤0.7%

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