USP 99% Ondansetron hydrochloride Hcl powder with CAS 103639-04-9
Ondansetron hydrochloride
Synonyms: ONDANSETRON Hcl
CAS: 103639-04-9
MF: C18H19N3O· HCl· 2H2O
MW: 365.85
Product Categories: Ondemet, Emeset, Emetron;Other APIs
Usage Antiemetic;Serotonergic receptor antagonist
Biological Activity Selective 5-HT 3 receptor antagonist (K i = 6.16 nM). Antiemetic; prevents emesis induced by cytotoxic drugs and radiation.
Used to treat vomiting caused by chemotherapy, radiotherapy and surgery
USP 99% Ondansetron hydrochloride Hcl powder with CAS 103639-04-9
| Package |
carton drum with two plastic bags inside |
| Net weight |
25KG/Drum |
| Storage |
Sealed in cool and dry place to avoid moisture and light |
| Shelf life |
2 years when properly stored |
| Lead time |
1~3 days after confirmation |
| Test Items |
Test Standard |
| Appearance |
White or off-white crystalline powder |
| Solubility |
Sparingly soluble in water and in alcohol;Soluble in methanol, slightly soluble in isopropy Alcohol and dichloromethane, very slightly soluble in Acetone, chlorofor and ethyl acetate. |
| Identification |
UV: Max 209,248,267,310nm |
| |
IR spectrum:Concordant with the working reference |
| |
Discrimination chloride: Forward Reaction |
| Water |
9.0-10.5% |
| Residue on Ignition |
≤0.1% |
| Heavy metal |
≤10ppm |
| Compound D Chromatographic purity |
≤0.1% |
| TLC max single impurity |
≤0.40% |
| Other single impurity |
≤0.20% |
| HPLC Impurity C |
≤0.20% |
| Imidazole |
≤0.20% |
| 2-methylimidazole |
≤0.20% |
| -Impurity A |
≤0.20% |
| -Other single impurity |
≤0.10% |
| -Total Impurity |
≤0.50% |
| Residual solvent Ethanol |
≤5000ppm |
| Assay |
98.0%~102.0% (on dried basis) |
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