99% USP40 Sleep Aid Powder CAS 73-31-4 Melatonine

• CAS No.: 73-31-4
• Formula: C13h16n2o2
• EINECS: 200-797-7
• Grade: Pharm
• Function: Other
• Certification: MSDS, FDA, GMP
• Model NO.: Melatonine
• Usage: Cosmetic Raw Materials, Pharm
• Raw Material: 73-31-4
• Transport Machine: Ordinary Goods Truck
• Appearance: White Powder
• Transport Package: Drum
• Specification: CP; USP; EP
• Trademark: Recedar
• Origin: China
• HS Code: 0000
• Production Capacity: 10t

Product Description

99% USP40 sleep aid powder CAS 73-31-4 Melatonine

 

99% USP CAS 73-31-4 Melatonine powder

Name: Melatonine
CAS: 73-31-4
MF: C13H16N2O2
MW: 232.28
EINECS: 200-797-7

The well-known function of melatonin is mainly to improve the quality of sleep (dosage 0.1~0.3mg), shorten the time to wake up and fall asleep before going to bed, and improve the quality of sleep. The number of awakenings during sleep is significantly reduced, the light sleep phase is short, and the deep sleep phase Prolonged, the wake-up threshold dropped the next morning. There is a strong function of adjusting the time difference.
The biggest feature of melatonin should be that it is the strongest endogenous free radical scavenger found so far. The basic function of melatonin is to participate in the antioxidant system and prevent oxidative damage to cells. In this regard, its efficacy exceeds all known substances in the body. The latest research proves that MT is the commander-in-chief of endocrine, which controls various types of body The activity of the endocrine glands. So as to indirectly control the functions of our whole body.
 

Function:
Prevent disease
Because MT can easily enter cells, it can take on the task of protecting nuclear DNA. If DNA is damaged, it can cause cancer. If there is enough Mel in the blood, it is not easy to get cancer.

Adjust the circadian rhythm
Melatonin is a hormone in the body that induces natural sleep. It overcomes sleep disorders and improves sleep quality by regulating people's natural sleep. The biggest difference between it and other sleeping pills is that melatonin is not addictive and has no obvious side effects. Oral 1-2 tablets (about 1.5-3 mg of melatonin) before going to bed at night, usually within 20 to 30 minutes, you can feel drowsiness, and melatonin automatically loses its efficacy after dawn in the morning, and you will not be tired or awake after getting up. But the feeling of coming.

Postpone aging
The pineal gland of the elderly gradually shrinks, and the secretion of Mel decreases accordingly. The amount of Mel required by various organs in the body is insufficient, leading to aging and disease. Scientists call the pineal gland the "aging clock" of the human body. When we supplement Mel from the body, we can set the aging clock back.

Regulatory effects on the central nervous system
A large number of clinical and experimental studies have shown that as an endogenous neuroendocrine hormone, melatonin has a direct and indirect physiological regulation effect on the central nervous system, has a therapeutic effect on sleep disorders, depression and mental illness, and has a protective effect on nerve cells. effect. For example, melatonin has a sedative effect, can also treat depression and psychosis, can protect nerves, can relieve pain, regulate the hormones released by the hypothalamus, and so on.

Regulating the immune system
Neuroendocrine and immune systems are interrelated, and the immune system and its products can change the function of neuroendocrine. The neuroendocrine signal also affects the internal immune function. In the past ten years, the regulation of melatonin on the immune system has attracted widespread attention. Studies at home and abroad have shown that it not only affects the growth and development of immune organs, but also regulates humoral and cellular immunity, as well as cytokines. For example, melatonin can regulate cellular immunity and humoral immunity, as well as the activity of a variety of cytokines.

Regulatory effect on the cardiovascular system
Mel is a light signal with multiple functions. Through its secretion changes, it transmits information about the environmental light cycle to the relevant tissues in the body. Make their functional activities adapt to changes in the outside world. Therefore, the level of serum melatonin secretion can reflect the corresponding time of day and the corresponding season of the year. Mel is mainly secreted at night and affects various endocrine and biological functions. The relationship between Mel and the circulatory system can be confirmed by the following experimental results: the increase in Mel secretion at night is negatively correlated with the decrease in cardiovascular activity; the pineal melatonin can prevent arrhythmias caused by ischemia-reperfusion injury and affect blood pressure control. Regulate cerebral blood flow and regulate the responsiveness of peripheral arteries to norepinephrine. Therefore, Mel has a regulatory effect on the cardiovascular system.
In addition, melatonin also regulates the human respiratory system, digestive system, and urinary system.
 

Package	carton drum with two plastic bags inside
Net weight	25KG/Drum
Storage	Sealed in cool and dry place to avoid moisture and light
Shelf life	2 years when properly stored
Lead time	1~3 days after confirmation

 
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Test Items	Test Standard
Appearance	White to off-white crystalline powder.
Solubility	Slightly soluble in water, soluble in acet-one ethyl ace-tate and meth-anol
Identification	IR
	UV
	HPLC
Chloride and sulfate	≤0.02%
Loss on drying	≤1.0%
Residue on ignition	≤0.1%
Melting point	117ºC~120ºC
Paticle size	≥98% pass 80 mesh
Tap density	≥0.45g/ml
Bulk density	≥0.35g/ml
Residual solvent	Ethanol ≤500ppm
Clarity and degree of opalescence of liquid	Clear in the 1% melatonin solution of ethanol or chloro-form
Heavy metals	Total	≤10ppm
	Pb	≤1ppm
	As	≤1ppm
	Hg	≤0.1ppm
	Cd	≤0.5ppm
Related compounds	Individual impurity	≤0.1%
	Total impurities	≤1.0%
Microorganism	Total plate count	≤1000cfu/g
	Yeast & Molds	≤100cfu/g
	E.Coli	Absent/10g
	Salmonella	Absent/10g
	S.aureus	Absent/10g
Assay (on dried basis)	98.5%~101.5%